Almost all U.S. LTL carriers use NMFC freight classes, although some are attempting to move to a dimensionally-based system.
Freight classification groups products based on similar density, stowability, handling and liability so carriers and shippers have an effective way of communicating the ease of transporting said freight.
Some items, such as car transmissions, have a specific class no matter how heavy or big they are. This is called a fixed class. Items can be assigned a fixed class if the value and transportability very rarely change.